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Irvine drug company will lay off 60% of workers, explore merger

IDM Pharma Inc., an Irvine biopharmaceutical company, plans to lay off 60 percent of its workforce worldwide as the company explores the possibility of a merger or sale, according to a regulatory...

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Biolase names interim CFO

Biolase Technology Inc., the Irvine maker of dental lasers, named its corporate controller, Frederick M. Capallo, as interim chief financial officer. The temporary appointment, effective Jan. 30, fills...

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Newport businessman settles insider trading case

The Securities and Exchange Commission sued Newport Beach resident Kent Barkouras today for insider trading in the stock of Mentor Corp. Without admitting fault, Barkouras settled the case for...

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Edwards loses patent claim against Cook Inc.

Edwards Lifesciences Inc. in Irvine has lost at least the first round in a legal claim against Cook Inc. for patent infringement. A U.S. District Court judge in northern California granted Cook’s...

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Allergan CEO got $11 million in ’07, up 8.5%

David Pyott, chief executive of Allergan Inc., received $11.2 million in salary and other compensation in 2007, up 8.5 percent from 2006, the Irvine-based maker of Botox said in its proxy statement...

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Valeant slashing 1,380 jobs, as new CEO planned

Valeant Pharmaceuticals of Aliso Viejo today announced plans for cutting 1,380 jobs as part of a radical corporate transformation that new Chief Executive J. Michael Pearson outlined in March. Valeant...

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Allergan’s sales, earnings jump — overseas

Botox-maker Allergan Inc. reported a 23 percent increase in first quarter sales and said its net profits soared 154 percent, mostly because of increased overseas sales that were amplified in value by...

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Allergan workers ask Congress to save their jobs

Register reporter Dena Bunis says more than 225 Allergan workers have signed a letter to House and Senate members asking them to get an R&D tax credit reinstated … “Hundreds of jobs at Irvine’s...

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Ex-CEO of Endocare pleads guilty to fraud

The former chief executive officer of Endocare Inc. agreed today to plead guilty to one count of criminal fraud in a scheme to defraud investors at the Irvine-based medical device company. Paul Mikus,...

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Allergan earnings up, outlook down

Allergan Inc., the Irvine maker of Botox and other medical products, reported  net income of $169.3 million for the quarter ending June 30, up 8.5% over the same period last year. But the company...

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AMO bought by Abbott for $1.36 billion

Advanced Medical Optics, the Santa Ana-based maker of Lasik laser surgery devices and eye care products, announced today that international health care giant Abbott will buy the company for $1.36...

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Irvine heart valve company sold for $700 million

Privately owned heart valve company, CoreValve Inc. in Irvine, is being bought for $700 million by Minnesota-based Medtronic Inc. The final price could increase with future milestone payments,...

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O.C. stocks gained almost 2% so far this year

An index of Orange County’s publicly-traded companies gained 1.78% in the first quarter of 2009, beginning a reverse of the 38% loss in 2008. Share values of 47 of 102 publicly-traded companies based...

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9 O.C. firms make Fortune’s best companies list

Nine Orange County companies made Fortune magazine’s 2009 top 1,000 list and four cracked the prestigious Fortune 500,  the magazine reported today. Ingram Micro Inc., the electronics distributor based...

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O.C. cancer drug company bought by Japanese firm

IDM Pharma Inc., an Irvine biomedical firm developing treatments for cancer, is being purchased by Takeda Pharmaceutical Co. Ltd. for about $67 million, the companies announced today. The $2.64-a-share...

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O.C. health tech firm sells for $16 million

Endocare Corp., an Irvine-based company that makes medical devices for the treatment of prostate cancer, announced today it is being acquired by HealthTronics Inc., for about $16 million. HealthTronics...

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Broadcom could raise bid for Emulex

Broadcom Corp. in Irvine could raise its $9.25-per-share hostile takeover bid for Costa Mesa-based Emulex Corp., according to an e-mail exchange in a regulatory filing released today. The possibility...

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FDA approves Allergan anti-sight loss drug

Allergan Inc. said today that the Food and Drug Administration approved a drug it developed to treat macular edema, a condition that can cause loss of central vision. Irvine-based Allergan says the...

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American Airlines to end all O.C.-Bay Area flights

American Airlines, which had been planning to cut five flights a day from John Wayne Airport to the Bay Area , now says it will end all service to San Francisco and San Jose on Nov 19. Tim Smith, an...

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Clarient buys cancer-test maker

Clarient Inc. of Aliso Viejo said it bought Huntsville, Ala.,-based Applied Genomics Inc. in an all-stock deal worth up to $17.6 million. Clarient Chief Executive Officer Ron Andrews said Applied...

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